OVERVIEW OF PICKED CHEMICAL COMPOUNDS AND INTERMEDIATES

Overview of Picked Chemical Compounds and Intermediates

Overview of Picked Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the treatment method of several myeloma. Its synthesis or examine is critical for making certain the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound while in the synthesis of imatinib, a drug that targets particular different types of cancer, including Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers for example breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their study is very important for optimizing the manufacturing system and making certain substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat 2-Butenoicacid breast most cancers, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the treatment of breast most cancers. Different intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers such as ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound 3-(4-Nitro-1-oxo-1 is involved in the synthesis of adamantane derivatives, which have many purposes, such as antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for sort two diabetes that inhibits the enzyme DPP-4 to regulate blood sugar concentrations.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of assorted gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication utilized to deal with style two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).

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